ATLANTA — A national HIV vaccine trial dubbed HVTN-505 (known as Life Forward in the Atlanta region) has been stopped as an oversight committee has determined in preliminary results that people were being infected with the virus despite being vaccinated, Georgia Voice and other media outlets reported. Many were known to have participated in the Washington area as well.
Participants were notified in late April. Human trials began in 2009. The trial was being conducted in 19 cities and had more than 2,500 volunteers. All participants had to be HIV negative, sexually active and circumcised, Georgia Voice reported.
The HIV vaccine trial was funded with $77 million from the National Institute of Allergy & Infectious Diseases (NIAID), part of the National Institutes of Health. In March, the trial had just finished enrolling the necessary 2,504 men who have sex with men and transgender people who have sex with men. Just weeks later the trial was called off after it was found that 41 of the 1,250 people who received the vaccine contracted HIV while just 30 of the 1,244 who received a placebo tested positive.
The volunteers are now finding out if they received the placebo or the vaccine. All will be followed for five years, the Voice reported. Those who received the placebo are eligible to participate in future HIV vaccine trials.
And there are many future HIV vaccine trials in the works. The Hope Clinic is currently enrolling in an early phase of a HIV vaccine trial named HVTN 092. So far, two people are enrolled.