National
HIV research sped development of COVID vaccine
Top NIH official says success in coronavirus will boost AIDS work
Since 1996, Carl W. Dieffenbach, who holds a Ph.D. in biophysics from John Hopkins University, has served as director of the Division of AIDS at the National Institute of Allergies and Infectious Diseases, which is an arm of the U.S. National Institutes of Health or NIH.
In a June 10 interview with the Washington Blade, Dieffenbach gave an update on the extensive, ongoing research into the development of an HIV/AIDS vaccine that he has helped to coordinate for many years, including current human trials for a prospective AIDS vaccine taking place in the U.S., South America, and Africa.
One thing he feels passionate about is a development not widely reported in the media reports about the successful development of the COVID-19 vaccine. According to Dieffenbach, the extensive research into an AIDS vaccine in recent and past years, while not yet successful in yielding an effective AIDS vaccine, helped lay the groundwork for the rapid development of the different versions of a COVID vaccine.
“Because my division runs the largest clinical trials program in the word, we jumped in with both feet to help with coronavirus disease for both vaccines and drugs and things like that,” he said. “And the platforms that were used – the way they are making the coronavirus vaccines – the RNA vaccines with Moderna – were first piloted by NIH and Moderna to try to make an HIV vaccine,” Dieffenbach says.
“So, in many ways, the work for the past 25 years that we’ve done in HIV vaccines sped the development of coronavirus vaccines,” he told the Blade. “And now it’s time to take what we’ve learned from coronavirus and take it back to HIV and start afresh or continue with what we have and build upon from what we have learned.”
Dieffenbach says one reason the development of a COVID vaccine came about before an AIDS vaccine, despite more than 20 years of AIDS vaccine research, is that the HIV virus is far more complex than the coronavirus, especially its ability to infect and remain embedded in the infected person for life.
“Back in 2007 we had the first hint that an AIDS vaccine might be possible with a study called RV144,” Dieffenbach says. “We spent 10 years trying to replicate that, and we just completed that study – a study called HVTN702. And it showed no efficacy,” he said, meaning it did not work.
“So that was a big disappointment to us,” he says “But in the meantime, we had pushed forward with the J&J [Johnson and Johnson pharmaceutical company] vaccine and are pretty far along. We’ll see what happens. We should know in the next several months whether the N26 version of an AIDS vaccine, and HIV vaccine works or not,” he says. “We’re very close to an answer.”
Washington Blade: Where do things stand in the development of an HIV/AIDS vaccine in light of Dr. Fauci’s statement a few weeks ago that the development of a COVID-19 vaccine could provide a boost to developing an AIDS vaccine?
Carl Dieffenbach: Sure. So, maybe I can start by introducing myself to you as a way of putting this into a context.
So, I’m the director of the Division of AIDS, which is the largest funder of HIV research in the world. And I report directly to Dr. Fauci. So, I’m responsible for all AIDS, all the time. And that is my passion and purpose in life. Part of that is working toward a safe, effective, and durable HIV vaccine, which has been one of the two most challenging questions left in science today. The other is a cure. They are connected in some ways.
So, with that as background, when coronavirus disease came along – because my division runs the largest clinical trials program in the world – we jumped in with both feet to help with coronavirus disease for both vaccines and drugs and things like that. And the platforms that were used – the way they are making the coronavirus vaccines – the RNA vaccines with Moderna were first piloted by NIH and Moderna to try to make an HIV vaccine. So, we’ve being working on that platform with Moderna for several years.
The leadership at Pfizer used to be part of a group at Penn, where we were also working with them. The J&J vaccine – we currently have in two Phase III clinical trials for HIV, one in sub-Saharan Africa, specifically in young women and the other one in the Americas in men who have sex with men and transgender individuals. Both of those Phase IIIs are moving along. The women’s study is fully enrolled. The men’s study was hit hard by COVID, but we worked through and will be fully enrolled by September.
One other vaccine just to talk about is the Oxford vaccine, the AstraZeneca vaccine. That is also using a platform at Oxford University, which has been used for HIV. So, in many ways, the work for the past 25 years that we’ve done in HIV vaccines sped the development of coronavirus vaccines. And now it’s time to take what we’ve learned from coronavirus and take it back to HIV and start afresh or continue with what we have and build upon from where we have learned.
Blade: That’s very interesting. But can we assume, then, from the clinical trials that have taken place for an HIV vaccine that they did not succeed in providing the immunity needed for an effective vaccine?
Dieffenbach: So, that’s exactly the problem we have. Back in 2007 we had the first hint that an AIDS vaccine might be possible with a study called RV144. We spent 10 years trying to replicate that, and we just completed that study – a study called HVTN702. And it showed no efficacy. So, that was a big disappointment to us. But in the meantime, we had pushed forward with the J&J vaccine and are pretty far along. We’ll see what happens. We should know in the next several months whether the N26 version of an AIDS vaccine, and HIV vaccine works or not. We’re very close to an answer.
Blade: So, the human trials are ongoing.
Dieffenbach: Oh, again – the study in young women in sub-Sahara Africa is fully enrolled. The men’s study will be fully enrolled in September. So, we have fought through the coronavirus epidemic to maintain, to nurse these trials along to make sure with the $100 million or so we’ve invested, that we didn’t want them to go down the drain literally because we lost too many people for follow-up. So, this was a herculean effort that has gone on all the time trying to do the vaccine studies for coronavirus disease, which we were also incredibly successful in.
Blade: Can we assume all of the people participating in the studies were HIV negative?
Dieffenbach: Yes, they’re HIV negative. They are people who are at risk. And also, in South America, for example, the major countries we’re in are Peru and Brazil. And they’ve had a strong research culture with us, going back more than a decade. For example, both of those countries played big roles in our studies of pre-exposure prophylaxis. A study called I-PREX that demonstrated that in men who have sex with men that [a PrEP drug] works well to prevent HIV acquisition in seronegative men who have sex with men.
So, we’ve been there. This is a really good setup for the countries, for the citizens that are in those countries that want to avail themselves to the research that has benefited everybody.
Blade: Among those who are participating in these ongoing AIDS vaccine trials, can we assume they cannot be taking the PrEP anti-retroviral drugs that have been shown to be highly effective in preventing HIV infection?
Dieffenbach: So, what we’ve done is we – everything is by conversation. So, when somebody who is interested in the study comes in, we talk to them. What is your chief interest in being in this study? And a lot of people want to be in the study because then they can access PrEP. They want to make it easier to get a hold of pre-exposure prophylaxis. They feel that is the best way that they can protect themselves.
So, in that situation, what we do is we take those people and link them to PrEP services where they can easily get PrEP in their community. So, first it’s taking care of those people. Then there are people who really have no interest in PrEP. And we actually counsel them every time they come in for a study. Are you sure you don’t want to access PrEP? And those are the people we then say, if you’re not interested in PrEP, what do you think about participating in a vaccine trial?
Because they’re the ones who have the most freedom of thought. They don’t have an opinion about the vaccine or about PrEP. So, those are the people we’ve been focusing on and enrolling. So, we’ve been very careful to make sure that if people wanted PrEP they not only have access, but they didn’t feel like somehow having to trade something in order to get it. The freedom to join a study should be a free choice. And it shouldn’t be a coercive thing to get PrEP. So, we just took that off the table and said if you’re truly interested in PrEP we can get you PrEP and make sure that was available.
Blade: So, in that case, if they choose PrEP they would not be in the vaccine trial?
Dieffenbach: You know, it’s interesting that you ask it in that way. Because you have relationships with your community, many of the investigators have reported that people will say, you know I tried PrEP and it wasn’t for me. It made me gaseous. It upset my stomach. I wasn’t myself. I tried it. I couldn’t make it work for me. I want to stop PrEP. Am I still eligible for the [vaccine] study? And the answer is of course. Many people are very happy on PrEP and they come in for visits occasionally and say this is working for me and just have the relationship with the doctors there, so it works. So, again, it’s about maintaining contact with your communities.
Blade: Can you tell a little about what happens next after people become part of an HIV vaccine trial. Do you have to keep in touch with these people, and do they have to get an HIV test periodically?
Dieffenbach: Exactly. So, the vaccine consists of a series of injections. It’s a mixture of vector systems that delivers a series of encoded HIV genes that are specifically designed to induce very broad immunity. There’s a whole computer-based process to design those components of the vaccine to make sure that it has sequence similarities with all the different versions of HIV circulating in the globe. And then at the end there is a protein boost. And we carry this out.
So, about every three to four months people come in. They get a shot. They fill out questionnaires. They give a blood sample. And they’re tested for HIV and are given a boost or a placebo. And they stay in touch with the clinic. They come in and out of the clinic. And the retention is quite high in these situations because people really like having the attention of the clinic available to them. It’s part of the community.
Blade: So, they go to a clinic for all of this?
Dieffenbach: It’s a research clinic. It’s not like a state-run health clinic. It’s a research clinic. Clinic is just a term for where people are seen.
Blade: Are any of these AIDS vaccine trials that are going on taking place in the United States?
Dieffenbach: Yes. So, the study is called Mosaico. And it’s HVTN706. And we have sites throughout the United States as well as South America. But that study is limited to men who have sex with men – the one in the United States.
Blade: Is it broader than just men who have sex with men in other countries?
Dieffenbach: No, so we decided to really focus on specific at-risk populations. So, in the Americas we chose to focus on men who have sex with men and transgender individuals. And sub-Saharan Africa we focused on young women because that is the target of the study population. So, 705 is all women in sub-Saharan Africa. And in the Americas in North and South America it is all men who have sex with men and transgender individuals.
Blade: Can we assume that the researchers that are doing these studies have a sensitivity of LGBTQ people? Is there still an issue where people worry about being outed as being gay or transgender?
Dieffenbach: So, many of the sites that we work with have been part of our system for over 20 years. And so, they are trusted members of the LGBTQ community within their cities and states. And ‘states’ is a literal term where it’s a state in Colombia or Peru or Brazil. And so, it is part of the fabric of the gay community in these places. Just like in San Francisco the San Francisco health clinic and the DCF clinics are part and parcel of everything the community does there.
And so, the lead physician in San Francisco is Susan Buchbinder. She has been a leader in health in this population for over 25 years or actually closer to 30 years at this point. We’re all getting old. Do you know that? So, we have been at this a very long time. And really have tried to build structures that are durable and therefore are reliable to the community. And that’s where we go back to the same groups time after time.
Blade: Have the locations of the vaccine testing sites been released publicly?
Dieffenbach: Yes, all of that is publicly available on clinicaltrials.gov. If you go into clinicaltrials.gov and search HVTN705 or HVTN706 you will get a version of the protocol, all the times it’s been modified, where we are – the protocol. All of that is public knowledge and available to you. HVTN705 is the women’s study. HVTN706 is the men’s study.
Blade: Is there a timeframe for when these latest vaccine studies might be completed?
Dieffenbach: I think within the next several months. We will get an answer out of the women’s study and then the men’s study is probably a year away. We were slowed a little bit because of COVID. We actually had to pause enrollment for several months. But we’re back on track.
Blade: Isn’t there a parallel research effort for an HIV/AIDS cure?
Dieffenbach: Yes, we have a very large program in cure research. It is a lot earlier in the discovery process and so it’s still very ‘researchy.’ And we have a very large program called the Martin Delany Collaboratories for Cure Research. Martin Delany was an activist who really pushed NIH in so many wonderful ways to really take the need for a cure seriously. His argument was a cure is the next logical step after effective anti-retroviral therapy. You cannot stop with one pill once a day. You’ve got to keep going. And he was pretty persistent. And unfortunately, he died several years go and we just thought the best way to honor him, and his memory was to name a program after him.
Editor’s note: Next week, in the second and final installment of his interview with the Blade, Dr. Dieffenbach discusses the progress in research and studies into an HIV/AIDS cure and explains from a scientific standpoint why an HIV vaccine is taking longer to develop than a COVID vaccine.
The White House
Trump-Vance administration ‘has dismantled’ US foreign policy infrastructure
Current White House took office on Jan. 20, 2025
Jessica Stern, the former special U.S. envoy for the promotion of LGBTQ and intersex rights, on the eve of the first anniversary of the Trump-Vance administration said its foreign policy has “hurt people” around the world.
“The changes that they are making will take a long time to overturn and recover from,” she said on Jan. 14 during a virtual press conference the Alliance for Diplomacy and Justice, a group she co-founded, co-organized.
Amnesty International USA National Director of Government Relations and Advocacy Amanda Klasing, Human Rights Watch Deputy Washington Director Nicole Widdersheim, Human Rights First President Uzra Zeya, PEN America’s Jonathan Friedman, and Center for Reproductive Rights Senior Federal Policy Council Liz McCaman Taylor also participated in the press conference.
The Trump-Vance administration took office on Jan. 20, 2025.
The White House proceeded to dismantle the U.S. Agency for International Development, which funded LGBTQ and intersex rights organizations around the world.
Secretary of State Marco Rubio last March announced the State Department would administer the 17 percent of USAID contracts that had not been cancelled. Rubio issued a waiver that allowed PEPFAR and other “life-saving humanitarian assistance” programs to continue to operate during the U.S. foreign aid freeze the White House announced shortly after it took office.
The global LGBTQ and intersex rights movement has lost more than an estimated $50 million in funding because of the cuts. The Washington Blade has previously reported PEPFAR-funded programs in Kenya and other African countries have been forced to suspend services and even shut down.
Stern noted the State Department “has dismantled key parts of foreign policy infrastructure that enabled the United States to support democracy and human rights abroad” and its Bureau of Democracy, Human Rights, and Labor “has effectively been dismantled.” She also pointed out her former position and others — the Special Representative for Racial Equity and Justice, the Ambassador-at-Large for Global Women’s Issues, and the Ambassador-at-Large for Global Criminal Justice — “have all been eliminated.”
President Donald Trump on Jan. 7 issued a memorandum that said the U.S. will withdraw from the U.N. Entity for Gender Equality and the Empowerment of Women and more than 60 other U.N. and international entities.
Rubio in a Jan. 10 Substack post said UN Women failed “to define what a woman is.”
“At a time when we desperately need to support women — all women — this is yet another example of the weaponization of transgender people by the Trump administration,” said Stern.
US ‘conducting enforced disappearances’
The Jan. 14 press conference took place a week after a U.S. Immigration and Customs Enforcement agent killed Renee Good, a 37-year-old woman who left behind her wife and three children, in Minneapolis. American forces on Jan. 3 seized now former Venezuelan President Nicolás Maduro and his wife, Cilia Flores, at their home in Caracas, the Venezuelan capital, during an overnight operation. Trump also continues to insist the U.S. needs to gain control of Greenland.
Widdersheim during the press conference noted the Trump-Vance administration last March sent 252 Venezuelans to El Salvador’s Terrorism Confinement Center, a maximum-security prison known by the Spanish acronym CECOT.
One of them, Andry Hernández Romero, is a gay asylum seeker who the White House claimed was a member of Tren de Aragua, a Venezuelan gang the Trump-Vance administration has designated as an “international terrorist organization.” Hernández upon his return to Venezuela last July said he suffered physical, sexual, and psychological abuse while at CECOT.
“In 2025 … the United States is conducting enforced disappearances,” said Widdersheim.
Zeya, who was Under Secretary of State for Civilian Security, Democracy, and Human Rights from 2021-2025, in response to the Blade’s question during the press conference said her group and other advocacy organizations have “got to keep doubling down in defense of the rule of law, to hold this administration to account.”
The White House
A full year of Trump and LGBTQ rights: all that’s been lost
White House since Inauguration Day has relentlessly attacked LGBTQ community
Uncloseted Media published this story on Jan. 20.
By NICO DiALESANDRO | One year ago today, Donald Trump was inaugurated as president of the United States for the second time. Since then, he and his administration have waged an all-out attack on the LGBTQ community by slashing crucial health and support programs, pressuring states to exclude transgender people from most aspects of life and erasing information about the community’s history. Here are all the biggest moves Trump has made against LGBTQ rights over the last 365 days.
Jan. 20, 2025 – Trump’s second first day
During his inaugural address, Trump says, “As of today, it will henceforth be the official policy of the United States government that there are only two genders: male and female.” Later that day, Trump signs “Defending Women from Gender Ideology Extremism and Restoring Biological Truth to the Federal Government,” an executive order that defines “sex” in federal law to mean biological sex at conception. It also eliminates federal recognition of trans identities, blocks gender self-identification on federal documents, ceases federal funding for gender-affirming care and restricts trans people’s access to bathrooms, prisons, shelters, and other government facilities that match their gender identity.
Trump also signs “Ending Radical and Wasteful Government DEI Programs and Preferencing,” an executive order that orders federal agencies to terminate diversity, equity and inclusion mandates, policies and programs. This order repeals a policy put in place by the Biden administration that created initiatives for the federal government to combat systemic barriers related to hiring on the basis of race, religion, income, gender identity, sexual orientation, and disability.
“We’re the party of common sense, you know, we don’t want to have men playing in women’s sports. We don’t want to have transgender operations for everyone,” Trump says at the Liberty Ball party that evening. Trump would go on to repeat the sentiment countless times throughout the year, including at press conferences with world leaders, in an interview with “60 Minutes” and even while deploying the National Guard in Washington.
Jan. 21, 2025 – The flurry of executive orders continues
Trump signs “Ending Illegal Discrimination and Restoring Merit-Based Opportunity,” another executive order that revokes a 1965 order which mandated affirmative action for federal contractors and required that they take steps to comply with nondiscrimination laws. The order violates the U.S. Supreme Court’s 2020 decision in Bostock v. Clayton County, which extended Title VII sex-based protections to trans people.
Nearly all LGBTQ- and HIV-focused content and resources are deleted from the White House’s website including the White House’s equity report, information about LGBTQ Pride Month and a fact sheet on expanding access to HIV prevention and treatment. In addition, the State Department removes its LGBTQ rights page, and the Department of Labor removes its LGBTQ workers page.
Jan. 28, 2025 – funding cuts
Trump signs “Protecting Children from Chemical and Surgical Mutilation,” an executive order that bars federal funding for gender-affirming care for minors and directs the Department of Health and Human Services to restrict insurance coverage for such treatments under Medicare, Medicaid and the Affordable Care Act. Hours after Trump signs the order, Uncloseted Media speaks with six LGBTQ kids to get their thoughts.
“For me, it’s definitely very frightening. Especially because right now I’m 16, and so, I’m going to become an adult over the course of his presidency. … And it’s really difficult, especially to plan for the future and have that lack of surety that I thought that I would,” Crow, who lives in Virginia, told Uncloseted Media.
Feb. 3, 2025
Mentions of LGBTQ people are erased or minimized across federal government websites, with a particular focus on trans and intersex people. The State Department first removes trans people in its travel safety guidelines, only mentioning the “LGB” community. As of publication, the web page has no mention of bisexual travelers either.
Feb. 5, 2025
Trump signs “Keeping Men Out of Women’s Sports,” an executive order that prohibits trans women and girls from competing on collegiate female sports teams.
Feb. 13, 2025
Under the direction of Trump’s executive order, the National Park Service removes references to trans and queer rights and history, including from the Stonewall National Monument pages. The “TQ” from “LGBTQ” is dropped in instances where the acronym is present. Protesters gather at the Stonewall National Monument in New York the next day to voice their outrage.
In an interview with Uncloseted Media, Stacy Lentz, co-owner of the Stonewall Inn, calls the removal a blatant attempt to rewrite history and exclude the very people who led the fight for equality.
Feb. 14, 2025
The U.S. withdraws from the United Nations LGBTI Core Group, which formed in 2008 and pledges to support LGBTQ and intersex rights by “work[ing] within the United Nations framework on ensuring universal respect for the human rights and fundamental freedoms for all, specifically lesbian, gay bisexual, transgender and intersex (LGBTI) persons, with a particular focus on protection from violence and discrimination.”
March 15, 2025 – illegal deportations
The Trump-Vance administration deports 238 Venezuelan migrants to CECOT, a maximum-security prison in El Salvador. The administration claims these individuals are affiliated with the Tren de Aragua gang. Andry Hernández Romero, a gay makeup artist seeking asylum, is one of the migrants with no criminal record. Hernández vanished from U.S. custody before his asylum hearing, and his lawyer asserts he was deported without due process.
On July 18, Hernández is returned to Venezuela along with 249 other migrants. The Department of Homeland Security dismisses abuse allegations of torture, sexual assault and other inhumane treatment.
April 2, 2025
U.S. Citizenship and Immigration Services updates its policy to recognize only two biological sexes, male and female, for immigration benefit requests and official documentation. This policy shift reverses previous efforts to accommodate nonbinary and trans individuals, as it removes the “X” gender marker option from immigration forms.
“By denying trans people the right to self-select their gender, the government is making it harder for them to exist safely and with dignity. This is not about ‘common sense’ — it is about erasing an entire community from the legal landscape,” says Bridget Crawford, director of law and policy at Immigration Equality.
April 3, 2025
In his first few months in office, Trump and his administration cancel over 270 National Institutes of Health grants focused on LGBTQ health, totaling at least $125 million in unspent funds. The cancellations disrupt research on HIV testing and prevention, AIDS, cancer, mental health and more.
The cuts scrap more than $800 million worth of research into the health of LGBTQ people. The cuts abandon studies of cancers and viruses and set back efforts to defeat a resurgence of sexually transmitted infections. They also eliminate swaths of medical research on diseases that disproportionately afflict LGBTQ people, including HIV/AIDs, various sexually transmitted infections and cancers.
June 2, 2025
Stanford begins suspending gender-affirming care for people younger than 19 in response to Trump’s executive order. Other major health networks and many regional centers across the country begin following suit.
Children’s Hospital Los Angeles announces they will be cutting off care for patients as old as 25 beginning in July, stating that they were left with “no viable alternative” because they could not risk any cuts to their federal funding.
June 6, 2025
Trump’s military ban begins, disallowing trans people from serving in all branches of the armed forces and removing those currently in the service. Those who do not identify themselves will have their medical records surveyed and be involuntarily separated if it is discovered that they are trans.
July 1, 2025
Trump’s “Big Beautiful Bill” is passed by Congress. The sweeping package of tax breaks that largely benefit the wealthy include major funding cuts to LGBTQ health care as well as a number of support programs that disproportionately serve queer people.
July 17, 2025
The Trump-Vance administration officially shuts down the LGBTQ-specific option on the 988 youth suicide hotline. This comes a year after data finds that 41 percent of LGBTQ youth seriously considered suicide. Notably, there are no plans to shut down the other targeted hotline options. Arden, who called when they were 16, told Uncloseted Media, “If it weren’t for the hotline, I would have killed myself.”
Aug. 4, 2025
U.S. Immigration and Customs Enforcement arrests 40-year-old asylum seeker Rickardo Anthony Kelly during a routine immigration appointment. Kelly, who survived being shot 10 times in Jamaica by attackers who targeted him for being gay, is released two weeks later and describes the conditions of the ICE facility as “unconscionable,” “inhumane,” and “horrific.”
Aug. 12, 2025
The State Department releases a revised 2024 human rights report that omits references to LGBTQ people and erases mentions of discrimination based on sexual orientation or gender identity. The report also removes critiques of governments for mistreating LGBTQ communities.
It excludes information about Hungary’s anti-LGBTQ laws that encourage citizens to report their LGBTQ neighbors and that ban depictions of homosexuality or gender transition in schools or the media.
Aug. 15, 2025
The Trump-Vance administration announces plans to eliminate gender-affirming care from the Federal Employees Health Benefits Program starting in 2026. The policy would also block access to hormones and surgeries for federal workers and their families.
Aug. 20, 2025
The media reports on court filings that reveal that the Justice Department issued subpoenas to hospitals for private medical records of LGBTQ patients 18 and younger. The DOJ requests billing data, communication with drug manufacturers, Social Security numbers and recordings from providers who treat gender nonconforming minors. Doctors across the country report threats and fear government retaliation.
“The subpoena is a breathtakingly invasive government overreach. … It’s specifically and strategically designed to intimidate health care providers and health care institutions into abandoning their patients,” says Jennifer L. Levi, senior director of transgender and queer rights at GLAD law, an LGBTQ legal group and civil rights organization.
Sept. 4, 2025
In response to a mass shooting in Minneapolis that was carried out by a trans woman, CNN reports that the DOJ is considering restricting trans Americans’ Second Amendment rights. The department aims to justify a firearm ban by declaring trans people mentally “defective,” building off of Trump’s trans military ban. The proposal sparks backlash from the National Rifle Association, who says in a statement that they will not “support … gun bans that arbitrarily strip law-abiding citizens of their Second Amendment rights.”
Sept. 12, 2025
The DOJ removes a study from its website showing that far-right extremists have killed more Americans than any other domestic terrorist group. The archived report disappears two days after anti-LGBTQ conservative activist Charlie Kirk is assassinated.
Sept. 22, 2025
White House Press Secretary Karoline Leavitt claims the administration is investigating why trans people are turning to “domestic terrorism,” despite no evidence of this. She calls anyone denying the false link “willfully ignorant,” despite the most recent data available from 2018 showing that trans people are four times more likely to be victims of violent crime when compared to cisgender people.
Sept. 23, 2025
Trump cancels a budget meeting and blames a potential government shutdown on Democrats’ support for trans-inclusive policies.
Oct. 1, 2025
FBI Director Kash Patel fires a trainee for displaying a Pride flag on his desk, labeling it an improper “political” message. The dismissal follows reports that pro-Trump appointees are combing internal FBI files to identify LGBTQ employees.
Oct. 3, 2025
Education Secretary Linda McMahon sends a nine-page proposal to nine universities that asks for a commitment to ban trans-inclusive facilities, define sex by “reproductive function” and limit race, gender or identity factors in admissions. The proposal calls for schools to revise their governance structures by “abolishing institutional units that purposefully punish, belittle, and even spark violence against conservative ideas.”
Oct. 10, 2025
The White House lays off more than 1,100 HHS employees. The Office of Population Affairs, which administered Title X family-planning networks, teen pregnancy prevention and LGBTQ health initiatives, is eliminated.
Nov. 6, 2025
The Supreme Court grants the Trump-Vance administration’s request to put a hold on federal rulings in Massachusetts, affecting trans and nonbinary people by preventing them from self-identifying correctly on their IDs, claiming to be in line with Trump’s “Defending Women from Gender Ideology Extremism and Restoring Biological Truth to the Federal Government” executive order. In her dissent, Justice Ketanji Brown Jackson writes, “This court has once again paved the way for the immediate infliction of injury without adequate (or, really, any) justification. Because I cannot acquiesce to this pointless but painful perversion of our equitable discretion, I respectfully dissent.”
Dec. 4, 2025
According to a memo obtained by NPR, the DOJ instructs inspectors to stop evaluating prisons and jails using standards designed to protect trans, intersex, and gender nonconforming people from sexual violence. This is in direct violation of the Prison Rape Elimination Act.
Dec. 18, 2025
HHS Secretary Robert F. Kennedy Jr. and Mehmet Oz, who leads Medicaid and Medicare, announce that HHS is heavily restricting trans health care; prohibiting Medicaid reimbursement for gender-affirming care for people under 18; and blocking all Medicare and Medicaid funding for hospitals that provide the care to minors.
Jan. 1, 2026
The Office of Personnel Management institutes policy changes that exclude coverage for “chemical and surgical” gender-affirming care in the FEHB and Postal Service Health Benefits plans for 2026, with narrow exceptions.
Jan. 7, 2026
Renee Good is shot and killed by ICE agent Jonathan Ross in Minneapolis. Good leaves behind a wife, Becca, and three children. In a statement, Becca remembers her wife:
“Renee lived by an overarching belief: there is kindness in the world and we need to do everything we can to find it where it resides and nurture it where it needs to grow. Renee was a Christian who knew that all religions teach the same essential truth: we are here to love each other, care for each other, and keep each other safe and whole.”
Days later, Trump tells reporters, “At a very minimum, that woman was very, very disrespectful to law enforcement. … It was highly disrespectful of law enforcement. The woman and her friend were highly disrespectful of law enforcement.”
Additional reporting by Hope Pisoni. Washington Blade photos by Michael Key and Michael K. Lavers.
Florida
DNC slams White House for slashing Fla. AIDS funding
State will have to cut medications for more than 16,000 people
The Trump-Vance administration and congressional Republicans’ “Big Beautiful Bill” could strip more than 10,000 Floridians of life-saving HIV medication.
The Florida Department of Health announced there would be large cuts to the AIDS Drug Assistance Program in the Sunshine State. The program switched from covering those making up to 400 percent of the Federal Poverty Level, which was anyone making $62,600 or less, in 2025, to only covering those making up to 130 percent of the FPL, or $20,345 a year in 2026.
Cuts to the AIDS Drug Assistance Program, which provides medication to low-income people living with HIV/AIDS, will prevent a dramatic $120 million funding shortfall as a result of the Big Beautiful Bill according to the Florida Department of Health.
The International Association of Providers of AIDS Care and Florida Surgeon General Joseph Ladapo warned that the situation could easily become a “crisis” without changing the current funding setup.
“It is a serious issue,” Ladapo told the Tampa Bay Times. “It’s a really, really serious issue.”
The Florida Department of Health currently has a “UPDATES TO ADAP” warning on the state’s AIDS Drug Assistance Program webpage, recommending Floridians who once relied on tax credits and subsidies to pay for their costly HIV/AIDS medication to find other avenues to get the crucial medications — including through linking addresses of Florida Association of Community Health Centers and listing Florida Non-Profit HIV/AIDS Organizations rather than have the government pay for it.
HIV disproportionately impacts low income people, people of color, and LGBTQ people
The Tampa Bay Times first published this story on Thursday, which began gaining attention in the Sunshine State, eventually leading the Democratic Party to, once again, condemn the Big Beautiful Bill pushed by congressional republicans.
“Cruelty is a feature and not a bug of the Trump administration. In the latest attack on the LGBTQ+ community, Donald Trump and Florida Republicans are ripping away life-saving HIV medication from over 10,000 Floridians because they refuse to extend enhanced ACA tax credits,” Democratic National Committee spokesperson Albert Fujii told the Washington Blade. “While Donald Trump and his allies continue to make clear that they don’t give a damn about millions of Americans and our community, Democrats will keep fighting to protect health care for LGBTQ+ Americans across the country.”
More than 4.7 million people in Florida receive health insurance through the federal marketplace, according to KKF, an independent source for health policy research and polling. That is the largest amount of people in any state to be receiving federal health care — despite it only being the third most populous state.
Florida also has one of the largest shares of people who use the AIDS Drug Assistance Program who are on the federal marketplace: about 31 percent as of 2023, according to the Tampa Bay Times.
“I can’t understand why there’s been no transparency,” David Poole also told the Times, who oversaw Florida’s AIDS program from 1993 to 2005. “There is something seriously wrong.”
The National Alliance of State and Territorial AIDS Directors estimates that more than 16,000 people will lose coverage
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