Arts & Entertainment
Working to end HIV
Foundation plans D.C. fundraiser to boost vaccine effort

Zachary Barnett will be in town next week for an HIV benefit at Mitchell Gold + Bob Williams. (Photo courtesy Mitchell Gold + Bob Williams)
Abzyme Research Foundation is partnering with Mitchell Gold + Bob Williams (1526 14th St., N.W.) and Cork Wine Bar for “Taste for Change,” a wine tasting and fundraising event to support an effort to end HIV/AIDS, on Tuesday at 7 p.m.
“We’re really excited to bring the presentation to D.C.,” says Zachary Barnett, executive director and found of ARF. “There’s a lot of energy … with the non-profit world and the government sector.”
ARF is a non-profit organization hoping to end HIV/AIDS by researching abzyme technology to produce the world’s first effective therapeutic HIV vaccine. Barnett compares this technology to the recent advancements and FDA approval for a shingles vaccine.
“Once you’re infected with chicken pox, you have that virus in your cells forever, but what the vaccine does … it’s effectively suppressing new outbreaks of infection,” Barnett says. “What we’re talking about is effectively the same. What if we could create a vaccine after you’ve already been infected, that would suppress the virus in your system.”
Barnett, infected by a partner in 2008, was recently named one of The Advocate’s “40 Under 40.” His nomination came at a time when he was considering being more public about his status. A friend had recently called him out on it.
“The chain of events was so weird,” Barnett says. “I kind of made the decision … and then The Advocate called me a couple days later … It was a really cool and serendipitous chain of events. I was happy to be given the opportunity to do it.”
Barnett started as a marketing and events consultant when he moved to New York City in 2006.
After finding out he was infected, Barnett brought his skills and passion to the world of HIV research advocacy.
“Fundraising and non-profit work, a lot of it is storytelling and communication,” Barnett says. “Creating event series and forums to talk to people and engage in communication is key to success, especially in the beginning.”
What started as a moment of personal crisis became a reason for Barnett to do more research on HIV/AIDS and its treatments, including the state of HIV/AIDS internationally. This research brought led him to a 2008 video by CBS, “Possible HIV Cure” with Dr. Sudhir Paul and his science team at University of Texas.
Barnett reached out to Paul and with the help of Marie LaFrance from Interview Magazine, threw a gala for the researcher and launched a PSA featuring Wilson Cruz, Justin Bond and Lady Bunny to engage supporters.
“I’m incredibly inspired by the doctors we’re working with,” Barnett says. “I think they’ve developed such an interesting, creative approach to battling the disease.”
Paul was first awarded a grant from the National Institute of Health in 1990. He’s published a paper identifying the CD4 binding site on the HIV outer coat as the “Achilles heel” of HIV. He has found that the human immune system has the innate ability to produce abzymes.
An abzyme, or an antibody-enzyme, is capable of starting the destruction of targeted molecules. A single molecule of an abzyme can trigger the destruction of thousands of target molecules and abzymes produced in animals have successfully blocked infection of human cells by genetically diverse HIV strains.
“This is completely hypothetical, and maybe getting ahead of ourselves, but … the abzyme technology has numerous applications,” Barnett says. “If this turns out to be a really dynamic technology that has the ability to make an impact on HIV, I’m excited to see where else we can take it.”
ARF’s goal is to raise $1.5 million for a FDA Phase I human trial, ideally in an HIV-positive population, to prove the E-Vaccine is safe and will induce antibodies that neutralize HIV in laboratory tests. According to its website, ARF, which has already covered its operation funding for the year, has raised $50,000 so far.
“We’re looking at a post-infection vaccine … exploring alternatives for daily anti-retroviral treatment. Can we develop a vaccine that will produce a robust antibody response in populations infected by HIV?,” Barnett says of the endeavor.
The Phase I human trial is the third milestone required to obtain FDA approval, according to an introduction brochure by ARF. The last being phase two and three efficacy trials to prove that the E-Vaccine will protect individuals who are at risk of being infected and prove control of virus infection occurs in infected individuals receiving the vaccine.
The organization has already secured a donor who will match the first $200,000 donated.
For more information on the organization or to donate, visit endhiv.com. The organization can also be followed at twitter.com/endhiv. To learn more about the fundraising event and to RSVP, email [email protected].
Photos
PHOTOS: The Bonnet Ball
The Bonnet Ball was held at JR.’s Bar (1519 17th St., N.W.) on Sunday.
(Washington Blade photos and video by Michael Key)











Books
Risking it all for love during World War II
New book follows story of Black, gay expat in Paris
‘The Remarkable Life of Reed Peggram’
By Ethelene Whitmire
c.2026, Viking
$30/308 pages
You couldn’t escape it.
When you fell in love, that was it: you were there for good. Leaving your amour’s side was unthinkable, turning away was impossible. You’d do anything for that person you loved – even, as in the new biography, “The Remarkable Life of Reed Peggram” by Ethelene Whitmire, you’d escape toward danger.

On Aug. 28, 1938, Reed Peggram boarded a ship from Hoboken, N.J., hoping to “become a proper gentleman” and fulfill his dreams. A prolific writer and Harvard scholar of comparative literature, he’d recently been awarded the Rosenwald Fellowship, which put him in the company of literary stars like Du Bois, Hurston, and Hughes.
Both Peggram’s mother and grandmother were then domestic workers, and they had big expectations for him. Reed himself was eager to study abroad, for professional and personal reasons; he was “determined to become a French professor and an accomplished linguist” and “He also hoped to find love.”
What better place to do it than in Paris?
Outgoing and confident, Peggram made friends easily and had no trouble moving “through the world of his white male peers.” Where he faltered was in his lack of funds. He relied on the kindness of his many friends – one of whom introduced Peggram to a “man who would become so pivotal in his life,” a Danish man named Arne.
Peggram and Arne had a lot in common, and they began to enmesh their lives and dreams of living in the United States. But there were complications: homosexuality was largely forbidden, World War II was in its early stages, and it quickly became apparent that it was dangerous to stay in Europe.
And yet, Peggram loved Arne. He refused to leave without him and so, while most visiting Black Americans fled the war in Europe, “Reed was trying to stay.”
There’s so much more to the story inside “The Remarkable Life of Reed Peggram,” so much to know about Reed himself. Problem is, it’s a long haul to get to the good stuff.
In her introduction, author Ethelene Whitmire explains how she came to this tale and yes, it needs telling but probably not with the staggering number of inconsequential details here. Peggram moved homes a lot, and many people were involved in keeping him in Europe. That alone can be overwhelming; add the fact that costs and other monetary issues are mentioned in what seems like nearly every page, and you may wonder if you’ll ever find the reason for the book’s subtitle.
It’s there, nearly halfway through the book, which is when the tale takes a tender, urgent turn — albeit one with determination, rashness, and a dash of faux nonchalance. Also, if you’re expecting an unhappily-ever-after because, after all, it’s a World War II tale, don’t assume anything.
Reading this book will take a certain amount of patience, so skip it if you don’t have that fortitude. If you’re OK with minuscule details and want a heart-pounder, though, “The Remarkable Life of Reed Peggram” might be a good escape.
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Theater
Iconic Eddie Izzard takes on 23 characters in ‘Hamlet’
Energized take on role offers accessible way to enjoy Shakespeare
‘The Tragedy of Hamlet’
Through April 11
Shakespeare Theatre Company’s Klein Theatre
450 7th St., N.W.
Tickets start at $90
Shakespearetheatre.org
Eddie Izzard is an icon.
Best known for her innovative standup and film roles, the famed British performer is also a queer activist who over the years has good-naturedly shared details from her decades long trans journey. What’s more, Izzard has remarkably run 43 marathons in 51 days for charity.
And now, Izzard finds a towering new challenge with the worldwide tour of “The Tragedy of Hamlet” (at Shakespeare Theatre Company’s Klein Theatre through April 11), in which she plays 23 characters (Hamlet, King Claudius, Queen Gertrude, the ghost, etc.) in a solo performance running just over two hours.
At a recent performance, Izzard, before slipping into character, appeared on the unadorned stage to say that though infused with comedy, “Hamlet” is definitely a tragedy, a story of a family and country both tearing themselves apart. She also warns that there’ll be a lot of breaking the fourth wall. After all, it didn’t exist in 1600 around the time when “Hamlet” was written.
The play unfolds in flurry of movement and scandal as the Danish prince begins to plot revenge after learning that his father, the old king was conspired against and murdered.
While some of Izzard’s character shifts are shown only by a subtle change in stance or modulation of voice, others are more obviously displayed like court sycophant Polonius walking with a stiff leg and mimed cane, or his ill-fated daughter Ophelia trotting girlishly across the upstage platform.
Delivered downstage at the intimate Klein venue, Izzard’s Hamlet soliloquies are performed with striking clarity. The one actor play is adapted and edited by Mark Izzard (the star’s older brother) and directed by Selina Cadell who successfully fosters the visceral connection between the actor and the house. Directly addressing an audience is something Izzard does exceedingly well. You feel as if she’s looking at/speaking to only you.
Cuts and choices are made that might not please traditionalists. The stabbing of eavesdropping Polonius might prove disappointingly underplayed to some. Whereas, the subsequent satisfying dual/death scene is long and precisely choreographed. Fear not, Izzard doesn’t flag a bit, not even when battling a cough (as was the case on the night of No Kings Day).
Not surprisingly, Izzard leans into the comedy. Her deliciously placed pauses, lines read ironically, and double takes, all gifts of comedy sharpened to perfection over a long career that kicked off as a street performer in the early eighties in London’s Covent Garden.
The play within a play scene finds Hamlet slyly rattling the conscience of King Claudius. As played by Izzard, it’s wickedly delightful and especially good. And the back and forth between the grave diggers done as a clever Cockney and his green assistant is a master class in how to play a Shakespearean clown.
Kitted out in a black peplum jacket over leather leggings and boots, Izzard gives gender fluid shades of contemporary diehard scenester and a Renaissance courtier. (Design and styling by Tom Piper and Libby DaCosta)
Attention has been paid to the blonde high ponytail, crimson lips and matching lacquered nails. The hands are important. Whether balled into fists or fingers fluttering, they’re in use, especially when playing Hamlet’s ex-friends Rosencrantz and Guildenstern (a clever surprise that can’t be spoiled).
Tom Piper’s set is wonderfully minimal. It’s an empty white walled space with three narrow windows that appear cut deeply into stone like those of a castle. These white flats serve as the ideal canvas for lighting designer Tyler Elich’s looming shadows, ghostly green light, and other unexpected flourishes of drama.
Izzard fills the stage. Her presence is huge, and her acting first-rate. At times, you forget it’s a one-person show.
I’d like to say, prior knowledge of the Bard’s best tragedy isn’t necessary to enjoy this fast-paced production. Despite a halved runtime and obscure words replaced with modern equivalents (“tedious old git” Hamlet says of Polonius), familiarity with the play is helpful.
With “The Tragedy of Hamlet,” Izzard secures a place among fellow queer Brits like Miriam Margolyes (“Dickens’ Women”), Sir Ian Mckellan (“Ian McKellen on Stage”), and more recently Andrew Scott (“Vanya”) in the solo players’ pantheon.
Izzard’s energized take on Hamlet is terrific. The way her powerful public persona bleeds into the work without taking over is exciting, and a uniquely accessible way to enjoy Shakespeare.
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