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WHO chief: COVID-19 ‘nowhere near over’ as monkeypox spreads

More than 750 monkeypox cases reported in U.S.

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Monkeypox virus (Photo courtesy of the Centers for Disease Control and Prevention)

World Health Organization Chief Tedros Adhanom Ghebreyesus told journalists at the regular weekly press briefing on Tuesday that rising COVID-19 cases are not only putting further pressure on already stretched global healthcare systems and workers but also triggering an “increasing trend of deaths.”

He reported that the Emergency Committee on COVID-19 last Friday concluded that “the virus remains a Public Health Emergency of International Concern.”

And while acknowledging that “we are in a much better position than at the beginning of the pandemic,” he stressed that new waves of variants demonstrate that the COVID-19 pandemic “is nowhere near over.”

The WHO chief outlined for reporters the interlinked challenges presented now by the virus, beginning with sub-variants of omicron, like BA.4 and BA.5, which continue to drive waves of cases, hospitalizations and deaths globally.

The WHO chief also pointed to diagnostics, treatments and vaccines that are not being deployed effectively.

“The virus is running freely, and countries are not effectively managing the disease burden based on their capacity, in terms of both hospitalization for acute cases and the expanding number of people with post COVID-19 condition, often referred to as long-COVID,” he said.

He highlighted a disconnect in COVID-19 risk perception between scientific communities, political leaders and the general public, describing it as “a dual challenge of communicating risk and building community trust in health tools and public health social measures like masking, distancing and ventilation.”

He then pivoted to the ongoing monkeypox outbreaks saying that there are currently 9,200 cases throughout 63 countries.

Next week the Emergency Committee for the disease will reconvene to examine trends, the success so far of countermeasures and next steps tackling the outbreak, he added.

In the meantime, he said that the WHO continues to battle the stigma around the virus, coordinate vaccine sharing, and drive forward research and development.

“I again stress that we must work to stop onward transmission and advise governments to implement contact tracing to help track and stem the virus as well as to assist people in isolation,” Tedros highlighted.

On Tuesday the U.K. Health Security Agency reported that as of July 11, there were 1,735 confirmed cases in the U.K. Of these, 1,660 are in England. The UKHSA also noted that a significant majority of cases are in reported in metropolitan London.

In the U.S., the Centers for Disease Control and Prevention says there are more than 750 monkeypox cases in the U.S. — across almost every state.

However, a stepped up response in ordering vaccines as well as testing has begun. In announcement Monday, the CDC noted that the Mayo Clinic Laboratories will begin testing for monkeypox using CDC’s orthopoxvirus test, which detects most non-smallpox related orthopoxviruses, including monkeypox.

“The ability of commercial laboratories to test for monkeypox is an important pillar in our comprehensive strategy to combat this disease,” said CDC Director Rochelle Walensky.  “This will not only increase testing capacity but also make it more convenient for providers and patients to access tests by using existing provider-to-laboratory networks.”

On June 22, HHS announced that five commercial laboratory companies would soon begin offering monkeypox testing. Since then, CDC has shipped the tests to the laboratories and their employees have been trained on their administration, among other steps.

Anyone with a rash that looks like monkeypox should talk to their healthcare provider about whether they need to get tested, even if they don’t think they had contact with someone who has monkeypox. Healthcare providers, nationwide, can order the orthopoxvirus test from Mayo Clinic Laboratories just as they normally would order other tests. The public will not be able to go to a Mayo Clinic laboratory and submit a specimen. Mayo Clinic Laboratories will use electronic laboratory reporting to report results to jurisdictions as outlined in the CDC reporting guidance.

CDC anticipates additional commercial laboratories will come online in the coming days, and monkeypox testing capacity will continue to increase throughout the month of July.  Healthcare providers can access information on Mayo Clinic Laboratories’ test at https://news.mayocliniclabs.com/*.

The latest CDC information on monkeypox is available at www.cdc.gov/monkeypox.

On the subject of COVID, the CDC cautioned Monday that BA.4 and BA.5 — subvariants of the omicron variant — now make up 80 percent of COVID-19 cases in the U.S., with BA.5 accounting for a majority of cases.

Early indications signal that BA.5 may have some increased ability to escape immunity, including from prior infections, meaning it has the potential to cause the numbers of infections to rise in the coming weeks.

This potential for increase is greatest where fewer people are up to date on their vaccinations and there is increased waning of immunity from vaccines, the CDC said.

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Health

MISTR announces it’s now prescribing DoxyPE

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MISTR, the telemedicine provider that offers free online PrEP and long-term HIV care in all 50 states, D.C., and Puerto Rico, announced it is now prescribing Doxycycline Post-Exposure Prophylaxis (DoxyPEP), an antibiotic that reduces bacterial STIs, including gonorrhea, chlamydia, and syphilis. Patients can now use MISTR’s telehealth platform to receive DoxyPEP online for free, according to a release from the company.

With this launch, MISTR plans to offer patients access to post-exposure care, in addition to its existing preventive and long-term HIV treatment options, which include PrEP and antiretroviral therapy (ART). This comes at a time when the rate of STIs continue to rise. In 2022, more than 2.5 million cases of syphilis, gonorrhea, and chlamydia were reported in the U.S; of that population, gay and bisexual men are disproportionately affected, the company reported.

“Despite an ongoing STI epidemic affecting the LGBTQ+ community, there are few resources available for this underserved, vulnerable community to get the preventative medication they need,” said Tristan Schukraft, CEO and founder of MISTR. “I’m proud that MISTR is democratizing access to PrEP, HIV care, and now DoxyPEP.”

An NIH-funded study published by the New England Journal of Medicine in April 2023 found that doxycycline as post-exposure prophylaxis, now known as DoxyPEP, reduced syphilis by 87%, chlamydia by 88%, and gonorrhea by 55% in individuals taking HIV PrEP, and reduced syphilis by 77%, chlamydia by 74% and gonorrhea by 57% in people living with HIV. 

MISTR is a telemedicine platform offering free online access to pre-exposure prophylaxis (PrEP) and long-term HIV care Visit mistr.com for more information.

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Health

UNAIDS to commemorate Zero Discrimination Day’s 10th anniversary

UN agency urges global action to protect human rights

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A UNAIDS anti-discrimination exhibit at Tocumen International Airport in Panama in 2018. (Washington Blade photo by Michael K. Lavers)

As the world marks the 10th anniversary of Zero Discrimination Day; UNAIDS is sounding the alarm on the increasing threats to human rights, calling for renewed efforts to protect the rights of all individuals as a fundamental step towards ensuring health for everyone.

Established by UNAIDS a decade ago, Zero Discrimination Day aims to promote equality and fairness regardless of gender, age, sexuality, ethnicity or HIV status. The progress achieved over the past years is now in jeopardy, however, due to rising attacks on the rights of women, LGBTQ people and other marginalized communities.

UNAIDS Executive Director Winnie Byanyima emphasized the critical link between protecting human rights and safeguarding public health. 

“The attacks on rights are a threat to freedom and democracy and are harmful to health,” she said in a press release. “Stigma and discrimination obstruct HIV prevention, testing, treatment and care and hold back progress towards ending AIDS by 2030. It is only by protecting everyone’s rights that we can protect everyone’s health.”

Despite challenges, there has been notable progress. 

At the onset of the AIDS pandemic more than 40 years ago, two-thirds of countries criminalized consensual same-sex sexual relations. They are now decriminalized in two-thirds of countries. An additional 38 countries around the world have pledged to end HIV-related stigma and discrimination, contributing to positive changes that include 50 million more girls attending school compared to 2015.

To sustain and enhance these advancements; UNAIDS urges global support for women’s rights movements, LGBTQ rights, racial justice, economic justice, climate justice and peace initiatives. By standing with communities advocating for their rights, the U.N. aims to reinforce the collective effort towards a more inclusive and equitable world.

Zero Discrimination Day is observed on March 1.

Events and activities that will take place around the world throughout the month will serve as reminders of the essential lesson and call to action: Protecting everyone’s health is synonymous with protecting everyone’s rights.

“Through upholding rights for all, we will be able to achieve the Sustainable Development Goals and secure a safer, fairer, kinder and happier world — for everyone,” said Byanyima.

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New CDC report finds transgender women at higher risk for HIV

More than 1,600 people in seven cities surveyed

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The Centers for Disease Control and Prevention in Atlanta (Photo courtesy of the CDC)

The Centers for Disease Control and Prevention issued a new study report this week that revealed that restricted by employment and housing discrimination and lack of access to needed gender-affirming healthcare for transgender women increasing the risk of contracting HIV. 

Researchers reviewed data from a 2019-2020 survey, the National HIV Behavioral Surveillance Among Transgender Women, which found that the demographics of HIV/AIDS have been disproportionally high, especially among Black and Latina trans women, who had experienced employment and housing discrimination coupled with lack of access to gender-affirming healthcare.

The Jan. 25 Morbidity and Mortality Weekly Report was based on data studies of more than 1,600 trans women in seven major urban locales. Participants from Atlanta, Los Angeles, New Orleans, New York, Philadelphia, San Francisco and Seattle were chosen by referrals from people and community-based organizations who knew or were part of the local population of trans women.

The study’s researchers noted: “Employment discrimination occurs at the overlapping nexus of poverty, homelessness, incarceration, health insurance, disability, food insecurity and survival sex work. These issues are interconnected.”

The study stated that trans women’s inability to access quality healthcare, including gender-affirming treatment or access to PrEP, and can expose them to potential incarceration as many turn to “survival sex work” and violence, which increases the risk of contracting HIV. 

The study’s author’s pointed out: “When economically marginalized transgender women are refused employment, this refusal cyclically contributes to economic hardships. This analysis …demonstrates the importance of transgender women working and living with dignity and without fear of unfair treatment.”

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